Apple pie @applepie@social.cleverlibre.org

It's that time of the year where I teach our 1st year #DataScience students about data *in the wild*

Do you want to always have access to all your notes and link your ideas in one app?

Then Obsidian sounds perfect for you

Here are 7 reasons why you should use Obsidian to take Notes during your PhD

A thread🧵

#academia #PhD #science #xp @OpenAcademics @AcademicChatter @obsdmd

Dear early career researchers: I have been writing papers for 17 years. A professional editor just sent back edits on a first draft of a 4 page text. Except for 5 lines, the whole document was red. This is how it goes! Don't feel bad if you get a massive amount of suggested changes on early drafts. The paper will most likely be better for it in the end.

12 positions for #DoctoralCandidates 🎓 in #Metabolomics #Bioinformatics #AnalyticalChemistry available in an EU 🇪🇺 #MarieCurie doctoral network!

Great supervisors, great projects! #TeamMassSpec

Please share with potential candidates!

Details: https://human-dn.eu/

As part of our NWO funded Open Science project we are improving our #raincloudplots package - We have a new beta R package release, and would love feedback on whether it installs/loads ok, any bugs, clarity of the vignette etc. Do tell us the good, bad and ugly #datascience #rstats #openscience #datavis #dataisbeautiful https://github.com/njudd/ggrain

Neutrophils are immune cells that do a lot of traveling (through the blood and into tissues) to get to sites of infection. Their large and stiff nuclei might it difficult for them to navigate through small spaces in tissues. So, how do they do it? Calì, Vargas, Viola, and colleagues showed that the signal that recruits neutrophils to target sites also makes their nuclei pliable so that they can squeeze through the gaps! Check out the study here: https://www.science.org/doi/10.1126/scisignal.abk2552 #science #immunology

Look at this gorgeous movie on Neutrophil (Green) talking with #EndothelialCell (Blue), #Pericyte (Magenta) & #MastCell (Cyan) in Venule during #Diapedesis 2 h post-TNFα challenge 🤩

Perivascular #MastCell IL-17A->
⏫MC-proximal venular #Pericyte/Mural cell (not #EndothelialCell) Surface presentation of ICAM1 & CXCL1->
⏫#Neutrophil #Diapedesis in subendothelial space

Dr. Mathieu-Benoit Voisin lab @NatureComms 2022 @RegisJoulia
https://www.nature.com/articles/s41467-022-34695-7

Hey, hey, it's Antarctica Day! 🇦🇶

What is Antarctica Day? I'm glad you asked!

#Antarctica #AntarcticaDay #Antártida​ #SWAIS2C

I was diagnosed with #HIV in 1998, when I was 30.
At the time, I did not expect to live to 50.
I’m 55 now.
HIV treatment works and it means I can’t pass it on - we call this #UequalsU.
HIV changed. Tell everyone.
#WorldAIDSDay #WorldAIDSDay2022 #AIDShistory #CantPassItOn #FightStigma

Dolichyl-diphosphooligosaccharide-protein glycosyltransferase noncatalytic subunit (DDOST) regulates the MITA/STING-mediated production of antiviral type I IFNs by inducing N-glycosylation at certain residues https://tinyurl.com/2u46aye4

#glycotime

I am a harmless wandering anthropologist, bringing 20 hours of free #CausalInference and #BayesianStatistics instruction to your door. From foundations of inference through DAGs, #MultilevelModels & poststratified causal effects to #GaussianProcesses, Bayesian imputation & ODEs. Theatrical trailer below. Playlist: https://www.youtube.com/playlist?list=PLDcUM9US4XdMROZ57-OIRtIK0aOynbgZN

Discovery of a novel human #protein that functions as #RNA #ligase first report of such #protein in higher #eukaryotes | RNA ligases play an important role in #RNArepair, thereby maintaining RNA integrity. Any malfunction in RNA repair in humans seems to be associated with #diseases like #neurodegeneration and #cancer Discovery of a novel human protein (C12orf29 on chromosome 12) as an RNA ligase....

https://www.scientificeuropean.co.uk/news-in-brief/discovery-of-a-novel-human-protein-that-functions-as-rna-ligase-first-report-of-such-protein-in-higher-eukaryotes/

I have been meaning to write about our whole blood microbiome paper across Indonesia since we first posted it... in April? And I keep getting sidetracked/burnt out, so it keeps falling to the wayside. But as they say, better late than never!

So, our study looking at what traces of microbiome diversity we can capture from whole blood RNA-seq. The final chapter of @twitter@KatalinaBobowik's PhD thesis. Read it here: https://www.biorxiv.org/content/10.1101/2022.04.24.489025v1

🧵1/n

A decade ago, we showed that >50% of plasmids lack protein coding genes for conjugation. Yet, they move. How? We now suggest that most plasmids in E coli and S aureus engage in conjugation. Many of them highjack components of plasmids that highjack themselves other plasmids to conjugate between bacteria. And these elements have the highest densities of antibiotic resistance genes!
Great work led by @M_AresArroyo now out!
https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkac1079/6849495?searchresult=1

Looking for a fast lightweight kmer counter for omics profiling in python?
Look no further you have MerCat2!
Congrats Jose Figueroa on your first paper!!!
#ncrckannapolis #uncc #teamraw #rawlab @UNCC_BIGScience @CLT_CCI
@unccharlotte
www.github.com/raw-lab/mercat2
https://www.biorxiv.org/content/10.1101/2022.11.22.517562v1

🧵1/ The Netherlands is the place to be if you want to study the #government's misuse of #AI in a democratic country.

A week or so ago there was some reporting on the Top 400, a #predictive #crime initiative by the City of #Amsterdam. They algorithmically create a list of the 400 youngsters they believe are most likely to commit serious crimes. The #police actively surveills them (including house visits!), even if they haven't committed any crimes at all.

https://www.trouw.nl/a-b4d1680d

Want to hear great #immunology talks from world-leading #LGBTQ+ #immunologists? Check out The STEM Village Immunology Seminar Series on our #Youtube channel! https://youtube.com/playlist?list=PLFW49k1qJ_3OwVW8ex773SUS1jiuG4NhE