CJ @flsounds@social.cleverlibre.org

I think I’m due for an #introduction! I’m an MD/PhD student at #uOttawa, doing my PhD in #neuroscience with Jean-Claude Béïque and Richard Naud. My work explores how uncertainty in reward feedback is processed in #prefrontal cortex, mainly in the context of #autism.

To do this, I use #behavior tasks in mice along with simultaneous in vivo two-photon calcium imaging. I also model #learning and #DecisionMaking using #ReinforcementLearning #RL.

Some of my other interests include patch clamp #ephys, post #stroke #synapse remodeling, #serotonin, #psychedelics and #consciousness.

Follow if you want to join me in finding and sharing interesting papers and ideas!

#NeuroscienceMigration #NeuroMastodon #ScienceMastodon

"Single-molecule magnetic tweezers to capture over a million individual transitions as a single talin protein unfolds and refolds under force in equilibrium. When observed at classically probed timescales, talin folds in an apparently uncomplicated two-state manner. As the sampling time extends from minutes to days, the underlying energy landscape exhibits gradually larger signatures of complexity, involving a finite number of well-defined rare conformations.[...]The physiological relevance of each distinct conformation can be connected to the binding of the cytoskeletal protein vinculin, suggesting an extra layer of complexity in talin-mediated mechanotransduction."
https://www.nature.com/articles/s41567-022-01808-4
#StructuralBiology #Talin #Vinculin #MechanoTransduction #MechanoBiology #Cytoskeleton

For those like me who have a #Wix website, this guide from @simoncox will help you get verified on #Mastodon. (Note you need a Wix plan with no ads for this to work!)

https://www.simoncox.com/post/how-to-get-your-wix-website-verified-on-mastodon

I have seen a few people doing this so I guess it's my turn. Here is a list of # I'm interested in.

Science:
#CellBiology
#MembraneTraffic
#MechanoBiology
#DevBio
#Growth
#Evolution
#Morphogenesis
#Microscopy
#ImageAnalysis
#BioPhysics
#Modelling
#SoftMatter

Other fields I am curious about:
#Epistemology
#HistoryOfScience
#SocialSciences
#GenderStudies

Fun&Games:
#Fantasy
#SciFi
#VideoGames
#BoardGames

I also love #SciCom and I'm always looking for new channels to communicate science.
Currently, I mainly use #SkypeAScientist, dedicated #Discord servers, and help when my institute organizes events.

I do believe I like and enjoy #mastodon even more than #reddit. (Not a #twitter user.)

Elon Musk foreign ties worth looking at, Joe Biden says

The plot thickens, as they say.

https://www.bbc.co.uk/news/business-63579775

#BBC #News #ForiegnTies #SaudiArabia #ElonMusk #joebiden

Just to give you an idea of how bad the whole "we block anyone who doesnt block who we block" has gotten, someone sent me this:

https://www.patreon.com/posts/74474015

I would **love** to give M.A a script that goes over all the instances in the fediverse and alerts them of every instance that doesnt follow the exact same block list as them and spit it out. I'm sure they will realize they have to block 99% of the fediverse... its getting laughable at this point.

Here is where you can find information about the pesticide testing requirements for cannabis in Canada:

https://canada.ca/en/public-health/services/publications/drugs-health-products/cannabis-testing-pesticide-requirements.html

I really have to say, of all the mass exodus onto this server we had over the years, this is one of the best. the quality and kindness of our new users are absolution exceptional. I appreciate all of you and welcome to the sane part of the internet!

More strike action in the UK, this country is heading for disaster.

PCS strike: 100,000 civil servants vote for walkout

https://www.bbc.co.uk/news/uk-politics-63586107

#BBC #News #Vote #CivilServants #Strike

Has anyone here contemplated using Roblox for work?

I manage remote software development teams who have never met face to face and I find that bringing people out of their shells is difficult, and activities like icebreakers can be invaluable for this.

Roblox games are very varied and the platform seems very flexible. And it got me thinking that maybe these icebreaker activities can be gamified. Imagine a Roblox game being used to estimate stories for a sprint for instance.

Anyway, does anyone know of anyone who has done this? I'd love to know how they found it.

#development #agile #gaming #roblox

"There is a theory which states that if ever anyone discovers exactly what the Universe is for and why it is here, it will instantly disappear and be replaced by something even more bizarre and inexplicable. There is another theory mentioned, which states that this has already happened." (Doug Adams)

For anyone interested, we have a chat room and matrix server for QOTO. Its usually not very active from now until about 10 hours from now, but the rest of the day me and a few people are active there.

Anyway, if anyone wants to join us and get a free account on our matrix server (it federates too so you can talk to and join rooms on other servers) then please do so, you are all welcome.

Here is the room, just register then follow this link:

https://element.qoto.org/#/room/#QOTO:qoto.org

Here we go, it’s #introduction time:

I’m currently a second year #neuroscience #phd student at the University of Pennsylvania! Broadly interested in #vision and #computation with my current research studying higher-level vision in the #treeshrew with the goal of learning about visual #development 🧠

I also love talking/reading/posting about #environmentalism and #sustainability 🌎, hanging out with my dog 🐕‍🦺, and playing soccer ⚽️

Looking forward to (re)connecting with other scientists on here!

My #introduction here:

I am 24 yo student of #communication Science at the university, also I have a #computer Science technical degree.

I have +5 years of experience #developing technology, mainly as developer but right now more into product.

I’m really interested about how technology affects our behavior trough communication.

If you're trying to find some of your favorite Twitter people who've migrated... @DataDrivenMD has made an awesome tool:
https://fedified.com

Fedified.com is a list of Twitter-verified accounts that have moved to Mastodon. This is a hand-curated list, so it's updated a few times daily. @DataDrivenMD https://fedified.com/

You can find people like @mollyjongfast @taylorlorenz and me. ☑️
#fedified #twittermigration