🎓 Dr. Freemo 🇳🇱 @freemo@social.cleverlibre.org

https://qoto.org/@freemo/102350040123388951

Long overdue on #introductions :

https://qoto.org/@freemo/102350040123388951

Long overdue on #introductions :

#Nature
#Science
#Buddhism
#Philosophy
#Psychology
#Psychotherapy
#Spirituality
#Religion
#Paranormal
#Cryptid
#Fiction
#Horror
#Fantasy
#Linux
#Computer
#Internet / #Web / #WorldWideWeb
#Space
#Tech / #AltTech / #Technology
#Security / #Privacy / #Anonymity / #Anonymous
#VideoGame / #Gaming / #Game / #Gamer / #Retro / #RetroGame / #RetroGaming
#Health
#Nutrition
#Fitness / #Bodybuilding / #Strength / #Training
#GeneticEngineering / #Cybernetics / #Cyborg / #TransHumanism / #TransHuman
#Existence / #Reality / #Existential
#SocialEngineering
#Culture / #Anthropology / #Society
#Drug / #Drugs / #Hallucinate / #Hallucination / #Hallucinogen / #LSD / #DMT / #Psilocybin / #MagicMushroom / #Mescaline / #Ayahuasca
#Mind / #Mental
#Emotion / #Feel
#MentalIllness / #MentalDisability / #Autism / #Bipolar / #Borderline / #Depression / #Depressive / #Mania / #Manic / #Schizophrenia / #Psychosis / #Sociopath / #Psychopath / #Sanity / #Insanity / #Insane

#environment #ecology #climate #science #global #dying #death

There's no 'deadline' to save the world. Everything we do now has to pass the climate test

https://www.theguardian.com/commentisfree/2020/mar/10/deadline-save-world-climate-test-crisis-governments#comments

Dear fediverse, I would love your input here.

I'm considering a research to understand the distribution and vulnerability level of microfungi by using some kind of proxy, like orchids to understand the mycorrhiza distribution and such, basically for conservation purpuses and IUCN listing.

I won't be too specific in my doubts not to influence you too much, but the data is pretty lacking and I'm not sure about how to proceed from here.

do you know if such a thing has been studied for any organism, not just for fungi?

Do you have any input or idea to throw at me?

What do you reckon a good proxy should have in this context?

I'm at an empasse with the practicality of the idea, so right now I'm wondering if to keep it and work on it or just drop it and move on.

🔸 How do we get the neurotransmitter out of the vesicle and out of the cell and make it able to go and affect another cell?

🔸 There is a cell membrane, but the cell also has a lot of other membranes that are inside. Inside in these things called organelles.

🔸 The fusion between two different membranes happens constitutively. And the challenge for a neuron is to stop that.
We can't have these vesicles fusing with the plasma membrane, with the cell membrane all the time. That would not work.

🔸 What we want to do is we want to make the vesicle fuse to the membrane **only when the action potential arrives** .

🔸 So the key to neurotransmitter release is two things:
1. We're going to suppress constitutive or ongoing release.
2. We are going to link the release that we want in the synaptic terminal to the action potential.

🔸 There is a molecule that suppresses constitutive release within the synaptic terminal.

🔸 When the action potential comes in, the membrane potential increases and it opens a particular type of ion channel that lets in calcium ions.

🔸 These are positively charged ions with two positive charges. And, these calcium ions are going to flood in to the synaptic terminal, and that is going to trigger release.

🔸 The release that happens of vesicles that contain neurotransmitters is only when the calcium concentration increases.

🔸 All that happens when the calcium concentration increases is that the vesicular membrane and the the cell membrane fuse.
And the calcium concentration only increases when the action potential arrives.

🖼️ Image source: screen-grab from https://www.coursera.org/learn/neurobiology/lecture/o4ZMY/neurotransmitter-release

the #QOTO ToS has been officially been updated after an in depth conversation with the community.

No policy changes occur, we have simply changed the wording to more accurately reflect the moderation policies we have always upheld.

Be kind, be respectful, and you will always have a place here!

You can see our new ToS here: https://qoto.org/about/more

#mastodon #fediverse #mastoadmin

#introductions.

I am new to this instance. I want to see what it is all about. Especially this huge character limit. How does it work applied to Federating?

I am a follower of Jesus, and I like to do some programming.

My other account is @masterofthetiger

#Introduction

I'm interested in:

#Mathematics #Macroeconomics #Engineering #ComputerScience #Programming

#Ecology #Environment #Democracy #Freedom #Equity #Liberal #Socialism #PostKeynesian

#Vegan

#FOSS #GNU #Linux

#Python #Graphics #WebDesign

I use:

#Debian #KDE #Firefox

#Inkscape #Gimp #Blender #VLC

#WordPress #Mastodon #PeerTube:

#Nextcloud #GitLab #Docker

#Fdroid

A #chinese
woman on the flight from #Bangkok to #Shanghai caused her dissatisfaction due to the stewardess's disinfection action, so she deliberately coughed at the stewardess and was stopped by the Thai flight attendant's throat, shouting: "I was wrong ! "

Does anyone have any pet #science topics not talked about? I'm not talking about fringe science. But science that isn't sexy to the mainstream.