kwitschas @kwitschas@social.cleverlibre.org

People are calling today the 30th birthday of the web; more accurately it’s the 30th birthday of CERN releasing the source code. I vividly remember websites being a curiosity among FTP servers, Usenet newsgroups, and gopher holes.

Here’s to this marvelous technology, Earth’s biggest Choose Your Own Adventure book, one of the most backwardly compatible systems ever built. Modern browsers may be elaborate interpreter-compilers but they still render the first site: http://info.cern.ch/hypertext/WWW/TheProject.html

#RosalindFranklin deserves to be remembered not as the victim of the double helix, but as an equal contributor to the solution of the structure. https://www.nature.com/articles/d41586-023-01313-5

Jobs at Yale: Postdoctoral and Postgraduate Positions in the Digital Ethics Center (DEC), Yale University. For more information:

- Postdoc: https://postdocs.yale.edu/postdoctoral-associate-positions-digital-ethics-center-dec-yale-university
- Salaries: https://postdocs.yale.edu/policies/postdoc-compensation

- Postgrad: https://postdocs.yale.edu/postgraduate-associate-positions-digital-ethics-center-dec-yale-university
- Salaries: https://postdocs.yale.edu/current-postgrads/salary-and-taxes

Sofia Jeppsson talks about philosophy of madness as part of the Mixed Bag series, using a book, a concept, a person, an article, and a surprise item to explore the topic. Enjoy!

#philosophy #psychiatry

https://awaisaftab.substack.com/p/mixed-bag-11-sofia-jeppsson-on-philosophy

Something of a pattern emerges. Nature publish a paper with weak statistics. 5 years later a replication fails.

https://pubpeer.com/publications/931266E207C5D34197797436DFA78D

Cui bono?

Upregulation of #connexin 30 in #astrocytes increases connectivity of #astroglial networks, but decreases synaptic transmission, altering #SynapticPlasticity & learning processes @EleonoreHardy_ @NathalieRouach @RancillacA &co #PLOSBiology https://plos.io/3UrHRMx

▓▓▓▓░░░░░░░░░░░ 28%

Quite happy to share this latest work from our lab. In this study, we have addressed an important question of general importance: if and how brain medications (such as anti-depression drugs) change brain over time. We addressed this by specifically investigating the impact of an important drug, Ketamine.
https://www.biorxiv.org/content/10.1101/2023.04.12.536506v1
#biorxiv #neuroscience #ketamine #brainplasticity
thread ....

Are grid cells used for navigation? On local metrics, subjective space, and black holes @NeuroCellPress
https://www.sciencedirect.com/science/article/pii/S0896627323002234

Join us! We are searching for a #postdoc to join a cool #CellBiology project working on intracellular transport vesicles. #microscopy #imaging and pure discovery

https://www.nature.com/naturecareers/job/12797417/research-fellow-cell-biology-/

#vacancy #ScienceMastodon #WarwickUni

Machine learning can easily produce false positives when the test set is wrongly used. Just et al in
@NatureHumBehav suggested that ML can identify suicidal ideation extremely well from fMRI and we were skeptical. Today retraction and our analysis of what went wrong came out.

Here is the retracted paper: https://nature.com/articles/s41562-017-0234-y and here is our refutation https://nature.com/articles/s41562-023-01560-6. If true, the paper's approach could revolutionize psychiatric approaches to suicide.

So what went wrong? The authors apparently used the test data to select features. Obvious mistake. A reminder for everyone into ML: never use the test set for *anything* but testing. Only practical way to do so in medicine? Lock away the test set till algorithm is registered.

Side note: it took 3 years to go through the process of demonstrating that the paper went wrong. Journals need procedures to accelerate this. Also, all the good things of this were by
@tdverstynen

I'm really trying to focus on work, but the cuteness overload is real

JOB ALERT: We’re hiring a researcher with technical expertise in assessing the performance and impacts of algorithmic systems to be part of our new, interdisciplinary Algorithmic Impact Methods Lab. Learn more and apply today. https://boards.greenhouse.io/datasocietyresearchinstitute/jobs/6672178002

A reminder that SUNY Geneseo is hiring a #tenuretrack Asst Prof of #Biology in #plantscience #plantsci with interests in #sustainability and #global issues. Join our welcoming department that values #Diversity and #Inclusion and #UndergraduateResearch
We're a #PUI in western NY. Please share widely!

Details: jobs.geneseo.edu/postings/4254

#botany #Plant #vegetation #aquaticplants #MarshMadness #Forest #ForestEcology #nativeplants