Nicola Romanò @nicolaromano@social.cleverlibre.org
Senior lecturer at ZJE and Edinburgh university.
I teach #imageanalysis & #dataanalysis with #RStats & #python. I study #heterogeneity in #pituitary (and other) cells.
Joined Oct 2022
Nicola Romanò
boosted
@arnaudlerouzic @datamaps @MichaelIngrisch @rstats Why? Because syntax preference is a highly personal thing. "Intuitive" and "human-readable" are subjective. Many people enjoy the dplyr approach to data wrangling, and it's made #rstats more accessible to a lot of people who don't come from a traditional coding background. I really like dplyr. I also really like data.table (but IMO it has a steeper learning curve for people without coding experience. I probably wouldn't teach it in a newsroom.)
Nicola Romanò
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@arnaudlerouzic @datamaps @smach @rstats
So what would you recommend then to teach beginners data visualization in R? I have yet to see the convincing one-liner base-R plot that is equivalent to what a freshly converted excel-user can produce with ggplot
Nicola Romanò
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@smach @datamaps is there really a big downside to load tidyverse instead of individual packages? If I'm writing a standalone script/analysis to do one thing then I just load the whole tidyverse so that I don't have to go back and load another library later. (Of course if I'm building a package, I wouldn't do that!)
Nicola Romanò
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Do you run or actively contribute to a reproducibility or open science initiative?
Join our virtual brainstorming event on "How to build, grow and sustain a reproducibility or open science initiative" (Nov. 22-23) to share your experiences. We'll discuss challenges and opportunities, explore solutions, and compile lessons learned to share with the research community.
All are welcome, including early career researchers from around the world.
Info & registration: https://www.bihealth.org/en/notices/how-to-build-grow-and-sustain-reproducibility-or-open-science-initiatives-a-virtual-brainstorming-event
Nicola Romanò
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One thing I love about Mastodon is the #Inclusive environment. So, to those who do not post alt text with their pics, I ask you to please learn how. Please include #blind people like me in your posts. If you're not sure how to write alt text, I can teach you how. And to those of you who *are* including alt text, thank you from the bottom of my heart!
Nicola Romanò
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Did you know that if you capitalize each word in a multi-word hashtag, #ScreenReaders can read them as words, but if you leave them lowercase, they can't? Well, now you know! So, for #accessibility, please capitalize words when there's more than one in a hashtag.
@corvina See, you always learn something new! Didn't know this had been done in mice as well!
There is some much older ('70s) yet still very interesting literature on similar experiments done on moths, showing you can reprogram the eclosion timing
This is a nice summary of some of those experiments!
https://www.ebrs-online.org/images/Documents/CC_Neuroendocrine.pdf
Nicola Romanò
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The advantage of living by a north facing shore on Skye...
Nicola Romanò
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Hello World! 👋
I'm Albert and I hope to reconnect with the #rstats and #dataviz communities on here.
Hopefully, this will be as much fun as Twitter was 🤞
About me: I'm a math PhD student and I post all kinds of daily R content. Specifically, I dabble in dataviz and Shiny web apps.
Toot toot! (What a great word. 😆)
Nicola Romanò
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I'm a Group Leader at HHMI Janelia working at the intersections of #ComputerVision, #MachineLearning, #DataScience, #Neuroscience, #Ethology & #HCI. I use #CV, #ML and tech to gain insight into biology. My most cited work involves animal tracking and behavior analysis. I love algorithms and trying to understand how, when, & why they work. But really I'm an engineer and want to solve problems however I can!
Outside work, I like sunshine, outdoors, #climbing, & #crosswords.
Nicola Romanò
boosted
#introduction #introductions Hello, I'm Arli, a #bioinformatician and popular science writer. As a scientist, I'm working on various project such as #COVID19 drug and vaccine design, #dengue drug and vaccine design, #cancer vaccine, #plasmodium protein domain annotations and others. I also wrote several popular science article. Here is one of my popular article: https://generasipeneliti.id/tulisan.php?id=ID4kquIFxQqNQk&judul=The-Role-of-Bioinformatics-in-Monkeypox-Outbreak-Surveillance-
@MartinHatch Oh, very simple! If you go in the preferences, under appearance you can choose a "Site theme". I am not 100% sure if all servers have the same themes... but I can see a "Mastodon Default Theme, Full Width (dark)" and a light counterpart that work well with the advanced web interface. Other styles seem not to work that well for me, but that might depend on browser, resolution etc, I guess. Easiest thing is to try and find one that you like!
@MartinHatch Also, using a "full width" theme with that helps a lot, otherwise content will not cover the whole page!
Nicola Romanò
boosted
#CysticFibrosis 📢 Anyone?
A little boost wouldn´t hurt I suppose
Thx
Nicola Romanò
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Very cool preprint from Bin Wu's lab.
They found bursting behavior of #translation by #SingleMolecule #mRNA #imaging in live cells, which is modulated by 5'UTR.
@biorxivpreprint
@schwiening Well, the thing with stress is that are oh-so-many protocols and different subtleties on how it is applied, that sometimes it gets really tricky comparing things. In general, people will talk about "acute stress" (i.e. a one-off event) vs chronic (i.e. multiple repeated events). So, yes 8 weeks is definitely chronic. Obviously, the extent of the effects of chronic stress are also species-specific; 2 weeks might be nothing for a human but a lot for a mouse!
In laboratory settings, you also often read about homotypic vs heterotypic chronic stress; the first indicates that the same stress is repeated multiple times and the other indicates a variable, often unpredictable stress.
I think it is important to also remember that while carefully designed experiments done in a lab setting can help understand the molecular mechanisms of stress, in humans, things are way more complicated. For example, there are social components that are not negligible; you might voluntarily inflict stress on yourself by setting yourself a deadline to do something or by deciding that you are going to go to that dinner party, despite disliking half of the people there!
@schwiening Good question! There does not seem to be stress-induced proliferation in corticotrophs, at least for acute stress. I think much of the control happens at the level of production and secretion of the hormone. In general, only a minimal % of the available hormone in each corticotroph is secreted in response to a stress, so the capacity of the gland is way way higher than what is normally needed.
If you think about it, it does make sense as stress is generally not something that is expected or that you can predict, so you need to have the ability to respond immediately, without having to wait for the hormone to be produced.
Some of my colleagues have recently written an article about this, which you might find interesting: https://academic.oup.com/endo/article/163/8/bqac089/6609891
The situation is slightly different for chronic stress where, depending on the strength of such stress, some proliferation might indeed happen.
Nicola Romanò
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The term “angina pectoris” comes from Greek “ankhonē” which means “strangling” & Latin “pectoris” meaning “chest”
The term has been used to describe a diagnosis rather than a symptomology.
Descriptions date back as far as 400BC when Hippocrates observed that some people experienced chest pain precipitated by cold winds.
Welcome to my tootorial #tutorial on a background to “angina pectoris”! #cardiology #medicine
@SteelFolk @Drosmel I am a big fan of open book exams where you are not asking to regurgitate facts but rather apply whatever we talked about and apply it to a practical situation. I think students appreciate this type of assessment because it's much closer to what they'll experience in real life.
Nicola Romanò
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🇳🇱
I mentioned this in a private message to someone recently about why a small handful of servers block qoto. I wanted to reiterate it here for the new comers on QOTO who dont know the history:
So there are some servers out there that demand every server int he network block every instance they do, and if a server doesnt block an instance they block then they block you in rettatliation.
Their reason for this is quite flawed but it goes like this.. If we federate with a bad actor instance and we boost one of their posts then their users will see it and defeat the purpose of the block. The problem is, this isnt how it actually works. If they block a server and we boost it, they wont see the boost, thats how blocks work.
The issue becomes even more complicated when you consider the fact that these servers, by virtue of their policy, have huge block lists where they block tons of major servers. So in order to satisfy them we too would have to block a huge number of servers.
This means you have a choice, you either join a server that isnt blocked, but has a huge block list themselves, or, you join a server that doesnt block and be blocked by a small handful of servers. Obviously that means on QOTO you will have bigger view of the world than you would on any of these others servers. In fact QOTO has onne of the largest federation footprints of any server in the network.
I want to also explain why we choose the decision we did. Years ago when this controversy started and servers across the fediverse started blocking there was a divide of people taking sides. WOTO was one of the few servers that didnt take sides and allowed people read content from any server (but with strict hate speech rules). This caused a huge influx of people,s pecifically from the LGBTQ community, onto our server. It turns out many people relied on us not-blocking for their physical safety. There were big name biggots (like milo yanappolus) who were on the network. They used their accounts here to watch his account for doxing so they could warn themselves and their community and protect themselves accordingly. In fact we added a feature just for them called subscriptions which allowed them to monitor accounts without following them so they could do so anonymously.
In tthe end for the safety of the LGBTQ community here we refused to engage in mass server blocking and instead encouraged our users to block servers on an individual basis and provided access to block lists for them to do so. But some really misguided servers blocked us anyway.
Thankfully the servers blocking us are few and far between and are limited to only the most excessive and aggressive block lists. As I said, QOTO has one of the largest federation footprints on the fediverse,
Senior lecturer at ZJE and Edinburgh university.
I teach #imageanalysis & #dataanalysis with #RStats & #python. I study #heterogeneity in #pituitary (and other) cells.
Joined Oct 2022
