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Hello #ScienceMastodon! I am an assistant professor in the MIT Department of Biology with our lab based at the Koch Institute. We build tools for high-throughput functional genomics in mice in order to understand and modulate regenerative capacity across mammalian tissues.

knouselab.org/

Tavo boosted

My (non representative) poll showed that people wouldn't accept a even when the dictator might align with one's values. Yet this is the reality in many tech companies. has seen a great example of why you shouldn't except a dictatorship even if your values align with the dictator's. Because there's no guarantee that a dictator will keep aligning with your values.

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Tavo boosted

Having run my own test mastodon server, I can tell you that boosting is REALLY important. That's how posts propagate between servers that are not federated together.

I may get a bit technical, and it can be hard to describe but it's something like this:

Let's say that you have 2 servers, A and B that are not connected. They have their own federated timelines that is vastly different.

let's assume they have their users @a@A and @b@B that are mutuals. If user @a@A sees something interesting on theirs federated timeline and boosts it, user @b@B will see that on their own home page. But more importantly server B will now know about and download that post, and everyone else on B server will be able to see that post on their own federated timeline!

And that's why you boost, guys! It helps posts to spread.

#FediTips

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Replicating experiments:

New preprint considers the “minimum viable experiment to replicate.”

“In this paper, we introduce the idea of a minimum viable experiment that needs to be identified in practice for replication results to be clearly interpretable.”

Devezer & Buzbas. (2022). Preprint: philsci-archive.pitt.edu/21475

#OpenScience
#MetaScience
#PsychMethods
#ReplicationCrisis
#PhilosophyOfScience
#PhilSci
@philosophy

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The top reasons graduate students are leaving academia 🏃‍♂️

1. The funding climate is discouraging

2. Too competitive/lack of jobs

3. Lack of work-life balance

"Less than half (48%) of respondents say that they would prefer, ultimately, to work in academia. That’s down from 56% in 2019"

"I don’t want this kind of life"

N = 3,200 international students that responded to a Nature survey

#macademia #phdlife @academicchatter

nature.com/articles/d41586-022

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Trying to replicate platforms we already have is a losing game.

This is the future, man. We can do cool shit that doesn't even have a name yet.

Idea 💡. Small fragments of DNA can work as logical gates. If the same is true for RNA, then the RNA of a virus could have encoded within an if and only if kind of logical structure. An early step of viral infection is the degradation of the host mRNA. Fragments that resulted from the degradation could interact with viral RNA changing it's structure and facilitating it's replication. Such mechanism could explain the seasonality of viral diseases.

running, achievement 

@clathrin congratulations, keep up the good work 😸

Tavo boosted

My #introduction to #mastodon:

I'm a biostatistician researching #statistics #biostatistics #epidemiology #publichealth. I primarily work on #bayesian methods for spatio-temporal & environmental #epi and #publichealth surveillance -- often for overcoming challenges related to imperfect data & small areas.

Most of my work is in #substanceuse & the opioid syndemic #hiv #HCV #overdose.

I've also been working on disease mapping models for environmental exposures associated with #ClimateChange.

Its almost done, updating hard drive, reinstalling everithing. :ablobdrum:

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Tavo boosted

Itga8-CreERT2, a novel tamoxifen-inducible -specific Cre🐭

Selective for Vascular over Visceral (GI/Airway...) SMC🤠

Critical comparison (+Aorta transcriptomes) vs Myh11-CreERT2

Dr. Qing Lyu & Joseph Miano labs Nature Cardiovascular Research 2022
nature.com/articles/s44161-022

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#SciFiSaturday

:_stars:

Once upon a linear time, aliens 👽 came and gave us the gift of immortality.

But over the eons, as our minds expanded, our bodies withered. So we enlarged our craniums and tinkered with our bodies. Replaced our worn out eyes and blood with a black synthetic.

And evolved into the aliens, 👽 who traveled back in time...

to give us immortality. 🙃

:_stars:

More #SciFi here! helfrich.ca/writing

#MicroFiction #SmallStories #TootFic #ScienceFiction #Writing #Paradox

Tavo boosted

Figured it’s finally time to do an #introduction. I am an #assistantprofessor at UC Santa Cruz. My lab studies interactions between #circadianRhythms and #infectiousDisease.
I study #streptococcus #pneumoniae #pneumonia #microbiology #immunology #innateimmunity using #mouse and #zebrafish models.
We know that #immunity to #pathogens changes throughout the day- my lab is trying to figure out how! #srbr #ZebrafishRock #metx
To learn more check out: kimmeylab.com/research

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#ChemMastadon Introduction!

Hi I’m Rakia (pronounced rock-yah) and I’m a fourth-year #chemistry PhD candidate in the Patterson Lab at UC Irvine.

I work on understanding how proteins influence the #crystallization pathways of #Metal-OrganicFrameworks using transmission electron microscopy #TEM and in-situ spectroscopy techniques.

I’m a #WorkingMom and passionate about #DEIB, #mentorship, and #outreach.

Looking forward to connecting with the larger #chemistryworld on Mastadon! 👩🏻‍🔬🧪

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Confirmed #COVID19 cases - #China 11/26/2022

Already taller than the April 2022 peak and no signs of slowing down!

Tavo boosted

RT @ChristosArgyrop@twitter.com

IMHO: the take home message of this paper is not that we should delay treatment, but that we should treat early, treat hard & possibly treat for longer. Some may say that this will avoid the creation of "hybrid" immunity, but given the health impact of breakthrough infections ...

🐦🔗: twitter.com/ChristosArgyrop/st

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