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#Sirt6 deacetylates #YAP & #TAZ->
⏬their transcriptional activities
⏬TGFβ1-induced Fibrotic reprogramming of #HepaticStellateCell
in diet-induced🐭#LiverFibrosis
TAZ seems more sensitive to Sirt6 than YAP🤓
Dr. Charlie Dong lab FASEB J 2022
https://faseb.onlinelibrary.wiley.com/doi/full/10.1096/fj.202200522R
