New paper from the Zerial Lab!
My colleagues and I have shown that apical projections across the bile canaliculi are load-bearing structures. These structures contribute to sustaining the anisotropic #growth of the nascent tube under increased intraluminal #pressure during #liver #development. These structures are supported by adherens #junctions and sealed by tight junctions.
I believe only @nunopmartins is here but if I am mistaken please tag any other author.
#CellPolarity #CellBiology #actomyosin #tubulogenesis
