Stunning work by @asramirez KP Locher and colleagues 👏 👏 👏 reveals the structure of the eukaryotic OST, explaining the evolution towards its specificity for an -Glc3 terminating LLO as an optimal substrate for turnover 🔥 🤩 ⬇️

https://www.nature.com/articles/s41467-022-35067-x

Ana recently gave a brilliant overview of her fantastic work at the @SfG Annual Meeting 👍 🤩

Imh this is a landmark paper for our understanding of protein N-glycosylation at the molecular level #glycotime