doctors in Norway have confirmed that the AstraZeneca vaccine has given three otherwise healthy non-elderly patients severe blood clots, and killed one of them. they have eliminated all other possible causes.

120.000 Norwegians have been vaccinated with AstraZeneca so far, meaning that 1 in 40.000 people have experienced this side effect.

the mechanism of action is that a severe immune response is triggered in the patients. some of the antibodies can react in such a way that they an activate the blood platelets, causing a blood clot to form. because these platelets have antibodies on them, they're removed from the blood stream, causing low platelet counts.

so basically, the platelets think they're plugging up a wound and start coagulating, causing clots to form.
some other medications can have the same side effect, which is why they suspected that the vaccine causes the same thing to happen.

it seems likely to me that all the vaccines could have this side effect, since they all cause antibodies to be produced, and it's the antibodies that cause the problem, not the delivery mechanism for the vaccine.
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@thor
> it seems likely to me that all the vaccines could have this side effect, since they all cause antibodies to be produced, and it's the antibodies that cause the problem, not the delivery mechanism for the vaccine.

i have heard the theory that nasal/oral vaccines are better wrt. side effects because they mimic the "natural" way pathogens get into the body vs. the "THEY ARE HERE!111" way of vaccines applied by injection. it seems that mucous membranes are a specialized part of the immune system.

en.wikipedia.org/wiki/Mucosa-a

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