"Dysbiosis in the gut microbiota impacts several systemic diseases. One possible mechanism is the migration of perturbed intestinal immunocytes to extra-intestinal tissues. Combining the Kaede photoconvertible mouse model and single-cell genomics, we generated a detailed map of migratory trajectories from the colon, at baseline and during intestinal and extra-intestinal inflammation."

#Immunology #MucosalImmunology #preprint

https://www.biorxiv.org/content/10.1101/2022.11.16.516757v1?med=mas