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'A pulse/chase experiment comparing chronically infected to treated animals showed that recently divided Ifng+ T cells, particularly IFN-γ+TNF+IL-2− T cells, are promoted by persistent infection. These data suggest that low-level persistent infection reduces CD4+ Tmem survival and multi-functional Teff but promotes IFN-γ+TNF+IL-2− Late Effector Memory and Terminally Differentiated Effector T cells and prolongs immunity.'
https://www.biorxiv.org/content/10.1101/2022.12.01.518804v1?med=mas
