"Using the CD4+ T cell-mediated disease experimental autoimmune encephalomyelitis (EAE), we show here that this process is markedly suppressed when TLR9 signaling is increased, without noticeably affecting the transcriptome of primed T cells, indicating a purely quantitative effect on CD4+ T cell expansion."

#Immunology #TLR #eae

https://onlinelibrary.wiley.com/doi/abs/10.1002/eji.202250059