"Detrimental combinations were associated with cytotoxic immune response in primary tumors, while metastases showed signs of immune evasion and ineffective antitumor immunity. On the contrary, beneficial combinations were associated with an active cytotoxic immune response only in metastatic samples."

#Preprint #HLA #Immunology #immunotherapy #TumorImmunity

https://www.biorxiv.org/content/10.1101/2022.11.16.516740v1