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"In the current study, we compared three different formulations for saRNA, a cationic polymer (pABOL12), a lipid emulsion (nanostructured lipid carrier, NLC13), and three lipid nanoparticles (LNPs). We investigated the early inflammatory profile after immunization and explored how that related to downstream adaptive immune responses. We then explored the role of RNA sensing on the adaptive immune response to vaccination."
#InnateImmunity #Immunology #RNAVaccine #Vaccines
https://www.cell.com/molecular-therapy-family/nucleic-acids/fulltext/S2162-2531(22)00316-X
@cyrilpedia thanks for posting this: an exciting paper 👍👍