'In the decade since the publication of CRISPR-Cas9 as a genome-editing technology, the CRISPR toolbox and its applications have profoundly changed basic and applied biological research. Wang and Doudna now review the origins and utility of #CRISPR-based genome editing, the successes and current limitations of the technology, and where innovation and engineering are needed.'

https://www.science.org/doi/10.1126/science.add8643