"With IL-8-humanized mouse strain, we demonstrate that IL-8-producing CD4+ T, myeloid, and tumor cells orchestrate myeloid-derived suppressor cell infiltration and angiogenesis, which results in enhanced tumor growth but reduced ICB efficacy."

#Immunology #Immunotherapy #cytokine

https://www.cell.com/cancer-cell/fulltext/S1535-6108(23)00077-6?dgcid=raven_jbs_aip_email