"Here, we show that glycolysis drives STING signaling to facilitate DC-mediated antitumor immune responses. Tumor-infiltrating DCs exhibited elevated glycolysis, and blockade of glycolysis by DC-specific Ldha/Ldhb double deletion resulted in defective antitumor immunity."
#Immunology #TumorImmunology #Immunotherapy #Metabolism
#InnateImmunity

https://www.jci.org/articles/view/166031