The jump to MHC alleles without described ligands is a promising sign that MixMHC2pred-2.0 could be a powerful tool for both basic and clinical research. Very curious to see if other groups validate and adopt it.

"Within humans, our work revealed that MHC-II binding motifs and MHC-II ligands could be accurately predicted even for alleles without known ligands. This is an important improvement of MixMHC2pred-2.0 compared with MixMHC2pred-1.2 and NeonMHC2, which were not applicable to most patients and could not be included in our benchmarks."
#Immunology

https://www.sciencedirect.com/science/article/pii/S1074761323001292?dgcid=coauthor#sec4