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Early days, but this is worth keeping an eye on:

"Other aspects of the donanemab trial are likely to be especially intriguing to Alzheimer’s experts. Patients stopped receiving donanemab and were switched to a placebo if their amyloid was cleared below a certain threshold. About half reached the threshold within a year, and their decline kept slowing even after they stopped receiving donanemab."

nytimes.com/2023/07/17/health/

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