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New anti-CD40L

'AT-1501, as a monotherapy and in conjunction with other immunosuppressive agents to prevent graft rejection in nonhuman primates. Encouragingly, AT-1501 promoted survival and function of islet and kidney allografts in cynomolgus and rhesus macaques, respectively, without evidence of thromboembolism.'

science.org/doi/10.1126/scitra

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