'We explored CDN-mediated immunity in 14 Drosophila species covering 50 million years of evolution and found that 2′3′-cGAMP and 3′2′-cGAMP failed to control infection by Drosophila C virus in D. serrata and two other species.'

https://www.cell.com/immunity/fulltext/S1074-7613(23)00362-X