"Our offices were just a short walk apart, and after meeting to discuss our suspicions, we began what has so far been a nearly 20-year collaboration to determine if phenylephrine was effective at the dosage available to consumers over the counter, and later, when we discovered it wasn’t, to petition the Food and Drug Administration to remove it from shelves."

https://www.nytimes.com/2023/09/29/opinion/cold-medicine-fda.html