"By his mid-20s, Mr. Holmes thought about what was ahead for him — sickle cell emergency after emergency, begging for help in Alabama hospitals that saw a Black man and assumed him to be a drug addict — and he started to think about ending his life. “Every time I tried anything, the disease would come and knock me away,” he remembered. “You get tired. You get worn out.”'

https://www.nytimes.com/2023/10/30/opinion/sickle-cell-gene-therapy-crispr.html