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That 'select' has been the problem for the last decade
"These results suggest that programmed cell death protein 1 blockade may benefit a select group of patients with brain metastases, and support further studies to identify biomarkers and mechanisms of resistance."

nature.com/articles/s41591-023

@cyrilpedia Also bringing up the problems with organ-specific microenvironments that have the power to be highly immunosuppressive: liver and brain. #Immunotherapy #organs #microenvironment

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