Fully Quantitative Measurements of Differential Antibody Binding to a Spectrum of SARS-CoV-2 Spike Proteins: Wuhan, Alpha, Beta, Gamma, Delta, Omicron BA.1, BA.4, BA.5, BA.2.75 and BA.2.12.1 https://www.medrxiv.org/content/10.1101/2023.01.11.23284431
@medrxivpreprint As the results the BA.1 – BA.5 mutations show increased potential for vaccine escape & the consequent loss of effectiveness of monoclonal antibody treatments ,However, some studies using different vaccine combinations have shown some improvement in the resulting neutralising antibody protection, & the new bivalent vaccines can provide better neutralising antibody binding