are there experiments you can only perform once ever? if so, how would you plan for and conduct them?

@2ck A bit of a dark direction to take this in, but...

Many people have done experiments that they could never repeat: for example, such experiments are an important source of knowledge about which plants are safe to eat and which are not.

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@eqyo heh. yeah, I'm thinking more like "which could we not repeat as a human species"

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