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New paper about #NMR assignment of a tau fibrils similar to those found in #Alzheimer'sdisease. Also includes ideas how to compare #NMR data with known #cryoEM structures. https://doi.org/10.3389/fnins.2022.988074
New paper about #NMR assignment of a tau fibrils similar to those found in #Alzheimer'sdisease. Also includes ideas how to compare #NMR data with known #cryoEM structures. https://doi.org/10.3389/fnins.2022.988074
@AnsgarSiemer It is a pity that these #ssNMR experiments do not distinguish different #tau #amyloid conformations, such as the #AD and #AGD folds. Would #NOE distance measurements help, or is that not possible for these samples?