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#PROTAB proteolysis-targeting antibody
An evolving #PROTAC variant
Use tumor-enriched cell surface #E3Ligase RNF43/ZNRF3 for targeted degradation of transmembrane proteins IGF1R/HER2/PD-L1
Dr. N. Agard & F. de Sousa e Melo labs @Nature 2022 @genentech
https://www.nature.com/articles/s41586-022-05235-6
