#EndothelialCell MEK1 #VascularMalformation

P1 topical 4OHT-induced mosaic EC MEK1 K57N transgene (what is the efficiency🧐)->
50% death by P30 +multiorgan VM (Arteriovenous malformation or other lesions) & Hemorrhage

Lesions composed of both mutant & WT EC

Dr. Patrick Smits lab Angiogenesis 2022
https://link.springer.com/article/10.1007/s10456-022-09853-6