IL-1β & Macrophage-like #SmoothMuscleCell/SMC-derived #FoamCell

scRNAseq👤calcified #Atherosclerosis (proximal vs core)->
Ligand-SMC receptor map + Mɸ-like SMC transcription network->
⏫IL1β-⏬STAT3

AAV9-Cas9-sgIL1β for🐭

Dr. Suxin Luo lab Comms Bio 2022
https://www.nature.com/articles/s42003-022-04255-2