Spatial Atlas of human Lung

Spatially-resolved multi-omics-> #AirwaySubmucosalGland-associated Lymphoid niche for IgA #PlasmaCell + T cells via CCL28/IL6/APRIL paracrine

5 locations, 13 patients

Systemic vs Pulmonary vascular trees

Immune recruiting venous NG2-ABCC9+ICAM1+ #Pericyte is abundant in CCL2/19/21 & CXCL12🤠

Love to dig into transcriptomes of systemic vs pulmonary #SmoothMuscleCell & pericytes along the bronchial tree😋

A spatially resolved atlas of the human lung characterizes a gland-associated immune niche

Love this powerful molecular micro-anatomy for human Lung👍

A great starting point for my Holiday-specific continued biomedical education on Lung🎄

Dr. Sarah Teichmann & Kerstin Meyer lab Nature Genetics 2022
https://www.nature.com/articles/s41588-022-01243-4