AT1 alveolar cell-derived #SonicHedgeHog recruits secondary crest myofibroblasts, a transient (arising e15.5; diminished P60) Force-exerting mesenchyme lineage, to build a Mechanical niche for🐭Lung #Alveologenesis

Dr. Edward Morrisey Lab @sciencemagazine 2021
https://www.science.org/doi/10.1126/science.abc3172

SCAPE: a powerful bioinformatic framework integrating scRNAseq+scATACseq to explore cell communication

Sender cell Transcription factor-Ligand - Receiver Receptor-Transcription factor