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@RonBeavis Not something I've ever thought much about before. MUC16 is a great guess just because it's so big, but my quick perusal suggests that the number of glycosites has not been experimentally measured.

@RonBeavis How many experimentally confirmed N-linked sites are on MUC16? I know there are quite a few sequons, but my understanding was that the N-glycan content was rather modest.

Place your bets

"To try to prove our own brilliance scientifically (before we are replaced by machine learning) is a challenge few editors would be able to resist, and we were no different. We thus set out to test our ability to predict citations of unpublished research papers submitted to The BMJ."

bmj.com/content/379/bmj-2022-0

Now you know: #Gender composition of #PhD degree earners in 2021: Selected fields with >500 degrees.
#highered @academicchatter

Announcing papertooter. Papertooter is a simple script that takes the URL of a biorxiv preprint, and posts the title and link to the paper on Mastodon using the Mastodon Python API. It also posts a unique hashtag it generates from the paper's DOI.

Feature requests and bug reports welcome.

github.com/idoerg/papertooter

I am thrilled to announce the publication of our most recent paper, which can be found at doi.org/10.1021/acs.analchem.2. We couple hydroxyl radical protein footprinting inline with weak anion exchange chromatography to measure the structural changes caused by phosphorylation/dephosphorylation of specific residues in a protein DURING a phosphatase reaction! This work opens up structural analysis of a wide variety of dynamic systems, where a particular conformer or proteoform cannot be isolated for high res structure elucidation. Very proud of this work, and of the group members that made it possible. @strucbio

What a tragedy that this good man, who has devoted his life to public service, who has made mistakes and learned from them, and who still expresses a profound understand of America’s public-health problems, should remain a target of vitriol from the worst among us. nature.com/articles/d41586-022

I will have PhD and RA positions open very soon. There's quite some flexibility for young researchers interested in experimental and #bioinformatics approaches in #MassSpectrometry #proteomics and #singlecell.

Please boost and spread. Feel free to get in touch.

Out today, my short piece in Nature Medicine about what scientists can do as authors to combat misinformation and disinformation about their own work.

rdcu.be/c1x7X

Notorious lickspittle Lindsey Graham doesn't seem to understand that we don't license expression in this country, and the reason for that is made plain by his suggestion: it would be used to punish expression that upsets the government.

📜 Our latest collaboration out in @embojournal!

In efforts led by Dr Ben Wang and Dr Julie Takagi, we identify Core 2 glycans as inhibitors of toxigenic conversion by a virulence-encoding phage in Vibrio cholerae.

#GlycoTime
💰 support: @snsf_ch & @UniBasel
embopress.org/doi/full/10.1525

@J_mey_sci Hey Jesse, there's a list here you can import as a CSV, or one by one, and some tips too. fosstodon.org/@makingions/1093

@neely See, I was gonna put a Kamala Harris "This is serious" gif at the end of my reply, but I couldn't!

@neely They need to integrate gifs into the standard apps and web interface if they want to attract the serious scientists...

Okay. Migrated from masthead.social to mastodon.social. Meanwhile, here's the Substack on my decision to leave Twitter.

popehat.substack.com/p/goodbye

The toughest thing about proving white collar crime, as I've learned from @Popehat is proving intent. I'd imagine that suspects having a groupchat called "Wirefraud" must make prosecutors positively *giddy*. (ht: @annmlipton ) afr.com/companies/financial-se

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