RT @RubinsteinJohn
New preprint!
Bedaquiline revolutionized MDR #TB treatment by inhibiting mycobacterial ATP synthase.
@CourbonGautier now shows how 2nd gen diarylquinolines from @TBAlliance improve affinity, & how squaramides discovered by @AstraZeneca target a new pocket
https://www.biorxiv.org/content/10.1101/2023.02.03.527018v1