For all electron microscopists out there:

"Crosshair, semi-automated targeting for electron microscopy with a motorised ultramicrotome"

Kimberly Meechan et al. 2022 @eLife from Yannick Schwab's lab at EMBL in collaboration with The Crick institute. elifesciences.org/articles/808

Presents a new method for reliably and "selectively targeting small regions of interest in a resin block by trimming with an ultramicrotome", powered by "user-friendly software to convert X-ray images of resin-embedded samples into angles and cutting depths for the ultramicrotome."

Reviewed by three outstanding electron microscopists: Christel Genaud, Song Pang, and Michaela Wilsch-Bräuninger.

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