Delivering ICIs to the brain

#InMice

"Assessment of the BBB/BTB physical and molecular properties, anti-PD1 penetration and uptake, and its impact on immune cell trafficking, along with monitoring of treatment response rates and durability are used to test our hypothesis and support the effective integration and translation to the clinics of brain cancer immunotherapy with MB-FUS and immune checkpoint blockade."

#Immunology #Immunotherapy

https://www.science.org/doi/10.1126/sciadv.add2288