CARTs in Lupus

'The re-emergence of B cells in these patients is another thing we’ll have to figure out. That just doesn’t happen in the leukemia CAR-T patients, and one obvious explanation might be that the memory B cells involved are in different tissues - bone marrow in the leukemia patients and other lymphoid organs in lupus. But that remains to be proven, and we’re going to learn some interesting things while doing that.'

https://www.science.org/content/blog-post/wonderful-progress-against-severe-lupus