ICYMI: Inhibition of translation termination by Drosocin, an antimicrobial peptide from fruit flies.
https://www.biorxiv.org/content/10.1101/2022.12.11.519952v1
Key result, the authors find mutations in Drosocin that improve its ribosomal inhibitory activity, suggesting it could be improved further.
@cyrilpedia @jhdcate @MarkHanson Yes, this is a really interesting result. I looked into trying to have Drosocin produced commercially a little while back and it was impossible to source because of the glycosylation...
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@marcdionne Was it going to cure male pattern baldness?
@cyrilpedia Is bacterial translation termination a well-characterized target in male pattern baldness?