'The following year, over a long weekend, Hardy and his colleague Gerald Higgins typed up a landmark perspective that used the term “amyloid cascade hypothesis” for the first time. “I wrote what I thought was a simple article saying, basically, if amyloid causes the disease in this case, maybe amyloid is the cause in all cases,” Hardy said. “I just typed it, sent it off to Science and they took it without any changes.”

https://www.quantamagazine.org/what-causes-alzheimers-scientists-are-rethinking-the-answer-20221208/