"Because Big Pharma is unconvinced of the profit potential, they're abandoning gene therapies — not just for SCID but for scores of other rare diseases — even when they know the cures work. As a result, kids like Jakob will needlessly suffer and die, denied access to a permanent fix for their illnesses. What's keeping Jakob isolated from the rest of the world, unable to play with a dog or make a friend, isn't his disease. It's the marketplace."

https://www.businessinsider.com/bubble-boy-disease-cure-but-drug-companies-wont-provide-it-2022-7