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'At least five of the winning models demonstrated accuracy exceeding 90% at detecting lung nodules. But to be clinically useful, those algorithms would have to perform equally well on multiple data sets.

To test that, Kun-Hsing Yu, a data scientist at Harvard Medical School in Boston, Massachusetts, acquired the ten best-performing algorithms and challenged them on a subset of the data used in the original competition. On these data, the algorithms topped out at 60–70% accuracy, Yu says. In some cases, they were effectively coin tosses'

nature.com/articles/d41586-023

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