Review at EJI

"Dysregulation or overproduction of IL-6 leads to autoimmune diseases such as multiple sclerosis (MS) and rheumatoid arthritis (RA), in which Th17 cells are considered to be the primary cause of pathology. Given the critical role of IL-6 in altering the balance between Treg and Th17 cells, controlling IL-6 activities is potentially an effective approach in the treatment of various autoimmune and inflammatory diseases."

#Immunology #Treg #Th17 #Autoimmunity

https://onlinelibrary.wiley.com/doi/full/10.1002/eji.201040391