'Molecular glue degraders are defined as the compounds leading targeted protein degradation (TPD) by creating novel ligase-substrate interactions. Here, we identified AK59 as a novel molecular glue degrader for STING.'

#Preprint #Immunology

https://www.biorxiv.org/content/10.1101/2023.02.08.527642v1?fbclid=IwAR0WPfDyebknVo9PiPLh54GcWR1M479oiFECuex81gmYLiFBMzpBZY8Vhvg