Fauci on AIDS before ART

"You’d try to treat the opportunistic infections, but it was like putting a bandaid on a hemorrhage because it was whack-a-mole. Their immune system was destroyed by this unknown virus. You would treat them for one opportunistic infection, and then another one would pop up, and then another one, until finally one would kill them."

https://www.nejm.org/doi/full/10.1056/NEJMp2300938?query=featured_home