"Transplantation of hNSCs has been shown to increase the number of CD4+CD25+Foxp3+ T regulatory cells (Tregs) in the spinal cords of murine models of MS, which is correlated with a strong localized remyelination response. However, the mechanisms by which hNSC transplantation leads to an increase in Tregs in the CNS remains unclear."

#immunology #Neuroimmunology

https://journals.aai.org/jimmunol/article-abstract/doi/10.4049/jimmunol.2200798/263631/Presentation-of-Human-Neural-Stem-Cell-Antigens?redirectedFrom=fulltext