Primer on the clinical uses of base editing tech @PLOSBiology
"In this Essay, we highlight base editing technologies and their development from bench to bedside. Base editing, first reported in 2016, is capable of installing C•G to T•A and A•T to G•C point mutations, while largely circumventing some of the pitfalls of traditional CRISPR/Cas9 gene editing."
#MolecularBiology #GeneTherapy

https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002071