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'Using RNAseq on blood from nine primate species exposed to bacterial lipopolysaccharides, we fit phylogenetic models and discovered hypermetric scaling in innate immune gene responses. We speculate that immune allometries may lead to asymmetrical expectations for virulence of zoonotic pathogens, such that diseases originating in smaller species may cause more severe immunopathology in larger species.'
#InnateImmunity #Inflammation #Sepsis #Immunology #Preprint
