'Using a high throughput compatible assay that measures real-time translocation of the glucose transporter glucose transporter 4 (GLUT4), we identified small molecules that potentiate insulin action. In vivo, these insulin sensitizers improve insulin-stimulated GLUT4 translocation, glucose tolerance, and glucose uptake in a model of IR'

#metabolism #insulin

https://www.cell.com/cell-chemical-biology/fulltext/S2451-9456(23)00190-3