I just breezed through 'The Knowledge Machine' by Michael Strevens. (Thanks to the recommendation from @NicoleCRust !)
Improbably, it's a pop science book about the philosophy of science. And it's quite good, even if you disagree with him.
Most radical is his "iron rule of explanation".
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A big problem is that the field has always been dominated by a focus on physics - whether or not you agree with it, a small book I recommend is Mayr's 'What Makes Biology Unique'
@cyrilpedia @NicoleCRust @DrYohanJohn Added to my reading list.
My take: biology is three fields inextricably intertwined: heredity, natural history, and physiology. Most practitioners are interested in one. They have to meet the standards of all three.
Physicists coming into biology fail most often by not meeting the standards of all three. (1/?)
@cyrilpedia @NicoleCRust @DrYohanJohn Example: a physicist who had done a bunch of work on gene expression levels in E. coli in high temperature hypoxic (trying to imitate the gut) and low temperature aerobic conditions (outside the gut) and tried to show the presence of adaptive mechanisms for each. Lovely data.
At the end I asked him what strain he had used. MG1655. The whole room sighed. The data was all useless because the natural history of MG1655 made it irrelevant.
@cyrilpedia @DrYohanJohn
Thanks!